Comparison of value of STER and ESD in treating upper gastrointestinal submucosal tu-mors based on the changes of gastrointestinal hormones
Objective o study and compare the value of STER and ESD in the treatment of upper gastrointestinal submucosal tumors(SMT)based on the changes of gastrointestinal hormones.Methods The clinical data of 70 patients with SMT admitted to department of gastroenterology of Anqing First People's Hos-pital from January 2020 to January 2023 were retrospectively analyzed,and the patients were divided into STER group(n=34,STER resection of tumor)and ESD group(n=36,ESD stripping of tumor)according to surgical methods.The clinical efficacy,perioperative indicators,wound recovery,gastrointestinal function re-covery,gastrointestinal hormones levels and complications were compared between the two groups.Results There was no statistical significance in clinical efficacy between the two groups(P>0.05).The intraoperative blood loss and postoperative hospital stay in STER group were less or shorter than those in ESD group,and the hospitalization cost was higher than that in ESD group(P<0.05).The wound length,wound healing time,first anal exhaust time and first defecation time were shorter in STER group than those in ESD group(P<0.05).The level of gastrin-17 in STER group was lower while the levels of pepsinogen Ⅰ and pepsinogenⅡwere higher than those in ESD group(P<0.05).There were no statistical differences in the incidence rates of surgical complications between the two groups(P>0.05).Conclusion Both ESD and STER have good clini-cal efficacy in the treatment of SMT.Compared with ESD,STER is more helpful to improve perioperative in-dicators and postoperative gastrointestinal hormones levels and shorten the rehabilitation process,and it has fewer postoperative complications,but the hospitalization cost is relatively high.It is recommended that doc-tors and patients should choose the surgical method according to the actual situation.
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