Objective To explore the changes in blood glucose levels and the related factors of lactate levels in children undergoing cardiopulmonary bypass (CPB).Methods A total of 103 patients who underwent cardiac surgery at Anhui Children's Hospital from January 2022 to December 2022 were selected and divided into two groups:CPB and non-CPB.The preoperative and postoperative blood glucose levels,postoperative lactic acid levels and related influencing factors were compared between the two groups.Results The postoperative mean blood glucose level in the CPB group was significantly higher than the preoperative mean blood glucose level,with a statistically significant difference (t=13.37,P<0.001).In the non-CPB group,the postoperative blood glucose level was also higher than the preoperative blood glucose level,with a statistically significant difference (t=3.60,P=0.001).There was no significant difference in the preoperative blood glucose level between the two groups (t=0.11,P=0.91),but the postoperative blood glucose level of the CPB group was significantly higher than that of the non-CPB group (t=7.55,P<0.0001).The postoperative lactate level in the CPB group was significantly higher than that in the non-CPB group,and the difference was statistically significant (t=4.16,P<0.001).There was also a significant positive correlation between lactate level and postoperative blood glucose level in both groups (P=0.042).Additionally,there was a significant correlation with the total time of external flow and the time of main pulmonary artery occlusion (P=0.049).Conclusion Blood glucose levels in pediatric patients undergoing CPB were significantly elevated.The postoperative blood glucose levels were found to be significantly correlated with lactate levels.
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