Predictive value of red blood cell and iron parameters in the third trimester of pregnancy for maternal outcomes in pregnant women with anemia in a high-altitude plateau region
Objective To explore the predictive value of red blood cell and iron parameters in the third trimester of pregnancy for maternal outcomes in pregnant women with anemia in a high-altitude plateau re-gion.Methods The clinical data of 390 pregnant women in a plateau area who were treated at Aba Tibetan and Qiang Autonomous Prefecture People's Hospital were retrospectively analyzed from January 2021 to Janu-ary 2023.Based on the presence of anemia during pregnancy,the pregnant women were divided into two groups∶the study group (pregnant women with anemia during pregnancy) and the control group (pregnant women with normal hemoglobin levels during pregnancy).The levels of serum red blood cells (RBC),hemo-globin (Hb) and serum ferritin (SF) were compared between the groups in the third trimester of pregnancy.Additionally,based on the pregnancy outcomes of the pregnant women,those in the study group were further classified into two groups:the pregnancy subgroup (women with normal pregnancy outcomes) and the adverse pregnancy subgroup (women with adverse pregnancy outcomes).Serum RBC,Hb and SF levels in the third trimester of pregnancy were compared between these two subgroups.Furthermore,ROC curve analysis was conducted to assess the predictive efficiency of serum RBC,Hb,and SF levels in the third trimester of preg-nancy on the pregnancy outcomes of pregnant women with anemia during pregnancy in a plateau area.Results Among 390 pregnant women in a plateau area,107 cases were diagnosed with anemia during pregnancy,re-sulting in an incidence rate of 27.43％.The levels of serum RBC,Hb and SF in the study group during the third trimester of pregnancy were lower than those in the control group (P<0.05).Out of the 107 pregnant women with anemia during pregnancy,65 had a normal pregnancy while 42 pregnant had an abnormal preg-nancy.Serum RBC and Hb levels in the normal pregnancy subgroup were higher than those in the adverse pregnancy subgroup (P<0.05),but there was no statistical significance in SF levels between the two sub-groups during the third trimester of pregnancy (P>0.05).Serum RBC and Hb levels in the third trimester of pregnancy showed a certain predictive value for pregnancy outcomes in pregnant women with anemia during pregnancy in plateau areas (AUC>0.5),with cut-off values of 312.00×1012/L and 80.53 g/L respectively.Conclusion The levels of RBC and Hb in pregnant women with anemia during pregnancy in plateau areas have a certain predictive value for adverse pregnancy outcomes.Clinically,it is necessary to enhance the monitoring of RBC and Hb levels in late pregnancy and provide timely supplementation to prevent adverse pregnancy outcomes.
Plateau areaAnemia during pregnancyPregnancyRed blood cellIron parameters
万方数据
维普
