Effects of different blood purification methods on β2-MG,CRP,SCr and UA levels in maintenance hemodialysis patients
Objective To analyze the effects of different blood purification methods on the levels of β2-MG,CRP,SCr and UA in maintenance hemodialysis patients.Methods From November 2021 to November 2022,90 patients with maintenance hemodialysis at our hospital were randomly divided into three groups:HD group,LD+HDF group and HD+HDF group with 30 cases in each group.The observational indexes of the three groups were compared.Results After 6 months of treatment,the LD+HDF group had a significant higher total clinical effective rate compared to the HD group,with statistical significance (P<0.05).Compared to before treatment,the levels of blood β2-MG,CRP,ESR,serum UA,SCr,Hcy,PTH,AGEs,and score of VAS in the three groups decreased after 6 months of treatment.In contrast,levels of serum BUN increased in the HD+HDF group compared to the HD group,with statistical significance (P<0.05).Conclusion The application of HD combined with HDF can improve the renal function of maintenance hemodialysis patients.It also helps reduce the inflammatory reaction and toxin index levels in patients and relieving the skin itching.This combination has shown to have a good blood purification effect.
万方数据
维普
