Analysis of 27639 cases of human papillomavirus genotyping detection
Objective To analyze the status of human papillomavirus (HPV) infection in the population of Luoyang.Methods To collect the results of HPV gene detection and clinical data of patients at the First Affiliated Hospital of Henan University of Science and Technology from the LIS system from June 28,2020 to November 30,2022.Cases with incomplete information were excluded.The differences in infec-tion between men and women,HPV positive rate,infection subtypes,and age distribution were analyzed.Results A total of 27639 cases were collected,with a higher positive rate in women (27.86％) compared to men (23.12％).There was a significant difference in the data (x2=7.404,P<0.05).The top five subtypes of in-fection in men were HPV16,HPV6,HPV11,HPV39,and HPV58,while in women they were HPV16,HPV52,HPV58,HPV61,and HPV51.The types of infection were mainly single and double infections,with a maximum of five infections detected in men and ten infections detected in women.In the male population,the youngest age was 16 and the oldest age was 68,there was no significant difference in the positive rate among different age groups (x2=10.906,P>0.05).In the female population,the youngest age was 14 and the oldest age was 89.The two age stages with higher positive rates were<20 years old (39.80％) and 60-69 years old (38.20％).There was a significant difference in the positive rate among different age groups (x2=259.381,P<0.05).Conclusion The research results show that the most common types of HPV infection in both men and women are type 16 and type 58,with female HPV infection being related to age factors.It is necessary to strengthen publicity and education in this area and raise public awareness and the importance of HPV infection.
万方数据
维普
