Clinical value of plasma related indicators alone and joint detection in early diagnosis of viral pneumonia
Objective To investigate the clinical value of plasma related indicators (neutrophil to lymphocyte ratio,NLR;platelet to lymphocyte ratio,PLR;lymphocyte to monocyte ratio,LMR) alone and joint detection in early diagnosis of viral pneumonia.Methods 55 patients with viral pneumonia and 55 pa-tients with bacterial pneumonia who were admitted to Daxing Teaching Hospital,Capital Medical University from April 2020 to April 2023 were selected as the research subjects.Meanwhile,110 healthy individuals were selected as the control group.NLR,PLR and LMR in the three groups were comparatively analyzed.Clinical indicators in patients with pneumonia were analyzed.The relationship between above-mentioned indicators and viral pneumonia,and the value of the three alone and their combination in early diagnosis of viral pneumoniawere discussed.Results NLR,PLR and LMR in the three groups were significantly different.NLR and PLR decreased in sequence,and LMR increased in sequence from the bacterial pneumonia group,the viral pneumo-nia group to the control group (F=54.911,69.849,685.249,P<0.05).CRP (C-reactive protein),N (neutro-phil) and M (monocyte) were lower in the viral pneumonia group when compared with those in the bacterial pneumonia group,with statistically significant differences (t=8.808,1.426,10.401,P<0.05).Blood pres-sure,respiratory rate,pulse,oxygen saturation,WBC (white blood cell count),L (lymphocyte),PLT (platelet) and urea nitrogen showed no statistically significant difference between the two groups (P>0.05).Regression analysis found that NLR,PLR and LMR were associated with viral pneumonia.For single diagno-sis of viral pneumonia,the AUC value of LMR was the highest (0.968).Its diagnostic sensitivity and specific-ity were 87.27％ and 96.36％.The AUC values of NLR and PLR were 0.809 and 0.754.The AUC,sensitivity and specificity of combination of the three were 0.691,100.00％ and 38.18％.Conclusion Patients with viral pneumonia have abnormally increased NLR and PLR,and abnormally decreased LMR.The three and their combination can be used for diagnosing viral pneumonia,and LMR has the best diagnostic performance.Com-bined diagnosis with the three indicators can improve the sensitivity.
Viral pneumoniaNeutrophil to lymphocyte ratioPlatelet to lymphocyte ratioLymphocyte to monocyte ratio
万方数据
维普
