Value of echocardiographic parameters combined with cTnI in evaluating myocardial injury in patients with severe pneumonia
Objective To investigate the value of echocardiographic parameters combined with troponin Ⅰ (cTnI) in evaluating myocardial injury in patients with severe pneumonia (SP).Methods 65 pa-tients with SP combined with myocardial injury who were admitted to Hongci Hospital in Tangshan City from March 2021 to March 2023 were selected as the combined myocardial injury group.Additionally,41 patients with simple SP were chosen as the simple SP group.Furthermore,120 healthy individuals who underwent physical examinations at our hospital during the same period were selected as the control group.Three groups of echocardiography parameters and cTnI levels were compared.The predictive value of echocardiography pa-rameters and cTnI for myocardial injury in SP patients were evaluated using receiver operating characteristic (ROC) curves.The influencing factors of myocardial injury in SP patients were assessed using multiple logis-tic regression analysis.Results LVEF levels:control group>simple SP group>combined myocardial injury group,LVEDD,LVESD,cTnI levels:control group<simple SP group<combined myocardial injury group,the difference was statistically significant (P<0.05).The area under the curve (AUC) of echocardiog-raphy parameters,cTnI,and their combined prediction for myocardial injury in SP patients have a 95％ confi-dence interval (CI) of 0.755 (0.704～0.807),0.859 (0.808～0.911),and 0.904 (0.853～0.956),respectively.The ratio of diabetes combined with myocardial injury,hypokalemia,and the time from onset to admission ≥ 1 week were higher than those of SP group alone,and the levels of CRP,WBC,PCT,CK-MB were higher than those of SP group alone,with statistical significance (P<0.05).Diabetes (OR=2.085,95％CI:1.429～3.044),increased PCT level (OR=2.385,95％CI:1.598～3.578),decreased LVEF level (OR=0.367,95％CI:0.238～0.566),and increased cTnI level (OR=3.377,95％CI:2.135～5.342) were independent risk factors for myocardial injury in SP patients (P<0.05).Conclusion Echocardiographic parameters and cTnI have a cer-tain value in predicting myocardial injury in SP patients.Their combined predictive efficiency is better.
Severe pneumoniaMyocardial injuryEchocardiographic parametersTroponin Ⅰ
万方数据
维普
