Objective To understand the human papillomavirus (HPV) infection status and geno-type distribution characteristics of female patients visiting Rizhao Traditional Chinese Medicine Hospital,and to provide data reference for early screening,prevention and treatment of cervical cancer and vaccination.Methods The test results of 7345 women who underwent HPV genotyping at Rizhao Hospital of Traditional Chinese Medicine from January 2020 to December 2022 were collected.The HPV infection rate,genotype dis-tribution and vaccine-protected HPV genotype infection were analyzed overall and in different age groups.Results Among the 7345 samples,1563 were found to be positive,with a positive rate of 21.28％.Specifi-cally,the positive rate of specimens from the gynecological outpatient department was 25.54％ (1,097/4295),and the positive rate of specimens from the health center was 15.28％ (466/3050).The positive rate of speci-mens from the outpatient department was significantly higher than that from the health center,and the differ-ence was statistically significant (x2=112.13,P<0.05).The infection rate of a single high-risk type was 11.79％ (866/7345) with the rate of multiple subtypes was 5.62％ (413/7345).The five high-risk types with the high-est infection rate were HPV16 (3.89％),HPV52 (3.05％),HPV58 (2.06％),HPV 53 (1.97％),and HPV 31 (1.54％).There were two peaks in HPV infection rates based on age group analysis:≤20 years (39.06％) and ≥ 61 years (27.24％).Genotype infections covered by the HPV nine-valent vaccine accounted for 64.43％.Conclusion The infection rate of HPV in female patients treated at Rizhao Traditional Chinese Medicine Hos-pital was 21.28％,with the main infection being the single high-risk type.The infection rate is highest among adolescent girls,and it is recommended that women of appropriate age receive the 9-valent vaccine.
关键词
人乳头瘤病毒/感染率/基因型分布/疫苗
Key words
Human papillomavirus/Infection rate/Genotype distribution/Vaccine
维普
万方数据