Efficacy of reduning combined with antibiotics on NLR and PLR in children with bronchoppneumonia
Objective To explore the efficacy of reduning combined with antibiotics on neutrophil/lymphocyte ratio (NLR),platelet/lymphocyte ratio (PLR) in children with bronchopneumonia (BP).Methods A retrospective analysis was conducted on the data of 84 pediatric patients with BP who were admitted to our hospital from April 2021 to February 2022.According to different treatment methods,they were divided into an antibiotic group (42 cases,treated with cefoperazone) and an antibiotic+reduning group (42 cases,treated with reduning in addition to the antibiotic group).The efficacy,disappearance of clinical manifestations,NLR,PLR,serum inflammatory indicators[interleukin-6 (IL-6),procalcitonin (PCT)]levels,and adverse drug reactions (ADRs) were compared between the two groups.Results The total effective rate was 95.24％ in the antibiotic+reduning group,which was higher than the 80.95％ in the antibiotic group,and the difference was statistically significant (P<0.05).The disappearance time of cough,body temperature,lung rales,and lung shadows in the antibiotic+reduning group was shorter than that in the antibiotic group,and the difference were statistically significant (P<0.05).After one week of treatment,the levels of NLR,PLR,serum IL-6,and PCT in both groups were lower than before treatment (P<0.05),with the antibiotic+reduning group were lower than the antibiotic group,and the difference were statistically significant (P<0.05).There was no difference in ADR between the antibiotic+reduning group (9.52％) and the antibiotic group (4.76％) (P>0.05).Conclusion The application of reduning combined with antibiotics for BP children has a positive effect.It can significantly reduce the levels of NLR,PLR,and serum inflammatory indicators,effectively promoting symptom resolution.
万方数据
维普
