Effect of self-shaping catheter intubation on levels of Cor,E and NA in infants with premature closure of cranial suture
Objective To explore the effect of self-shaping catheter intubation on the levels of cor-tisol (Cor),epinephrine (E) and norepinephrine (NA) in infants with premature closure of cranial suture.Methods According to the random number table,76 cases of children undergoing craniosynostomy under gen-eral anesthesia at the Children's Hospital Affiliated to Nanjing Medical University from December 2020 to De-cember 2021 were divided into the control group (38 cases) and the observation group (38 cases).The control group was intubated with intubation forceps,while the observation group was intubated with self-shaping cath-eter.The intubation-related indexes,laryngoscope exposure classification,and the changes of ean arterial pres-sure (MAP),heart rate (HR),blood oxygen saturation (SpO2) m after induction (T0),glottis exposure (T1),1 min after intubation (T2) and 3 min after intubation (T3) were recorded in both groups.Changes in serum Cor,E and NA in the two groups were also measured.Results The intubation time in the observation group was shorter than that in the control group,and the success rate of the first intubation was higher than that in the con-trol group,with statistical significance (P<0.05).There was no significant difference between the two groups (P>0.05).The HR and MAP of the children in T0～T3 groups increased and then decreased.At T2,the HR and MAP in the observation group were lower than those in the control group,with statistical significance (P<0.05).Compared to T0,the levels of serum Cor,E and NA in in both groups increased by T3,but the levels in the observation group were lower than those in the control group,with statistical significance (P<0.05).Conclusion Compared to the intubation assisted by intubation forceps,using a self-shaping catheter for nasotracheal intubation in infants with premature closure of cranial sutures can shorten the intubation time,increase the success rate of the first intubation,and result in relatively stable vital signs for the children.Additionally,this method can help lower the stress response in these infants.
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