Objective To explore the HPV infection situation and TCT results analysis in female health examinations at a tertiary hospital in Beijing,so as to provide a reference for the prevention and treatment of cervical cancer in the region.Methods The results of HPV and TCT tests in 10124 women who underwent health check-ups at China-Japan Friendship Hospital from July 2022 to September 2023 were retrospectively analyzed.Results Among the 10124 women who underwent physical examination,the HPV positivity rate was 7.34％.The difference in HPV positivity rate among different age groups was statistically significant (x2=29.721,P<0.001).The top five high-risk HPV subtypes are HPV-52,HPV-58,HPV-51,HPV-16,and HPV-39.The positive rate of TCT results was 2.49％,≥ 61-year-old individuals had the highest proportion of ASC and HSIL,while those aged 21-31 had the highest proportion of LSIL.As cervical lesions worsen from ASC to LSIL to HSIL,the positive rate of HPV gradually increases (51.41％,70.18％,and 88.89％).The difference in HPV positive rate between different degrees of cervical lesions is statistically significant (x2=485.453,P<0.001),as well as the difference in the types of HPV infection between different degrees of cervical lesions (x2=18.943,P<0.001).Conclusion The severity of cervical lesions is worsening,and the rate of HPV infection is increasing.Therefore,it is crucial to emphasize cervical cancer screening among women of appropriate age in this region.
关键词
高危型人乳头瘤病毒/HPV亚型/TCT检测/健康体检人群
Key words
High-risk human papillomavirus/HPV subtypes/TCT detection/Healthy physical examination population
维普
万方数据