The correlation between the new standard of MHR,MPV and ECG and left ventricular hypertrophy in patients with essential hypertension
Objective To investigate the relationship between the monocyte to high⁃density lipo⁃protein cholesterol ratio(MHR),mean platelet volume(MPV),the new ECG standard and left ventricular hypertrophy(LVH)in patients diagnosed with essential hypertension(EH).Methods Data from 100 EH pa⁃tients admitted to Nanjing Second Hospital from February 2021 to December 2023 were retrospectively ana⁃lyzed.The patients were divided into two groups:those with left ventricular hypertrophy(LVH group,38 cases)and those without LVH group(non⁃LVH group,62 cases)based on left ventricular mass index(LVMI).General data,MHR,MPV,and a new standard of electrocardiogram(SD+SV4)were compared be⁃tween the two groups.Pearson correlation and binary logistic regression were used to analyze the relationship between MHR,MPV,SD+SV4 and LVMI in EH patients and the influencing factors of LVH in EH patients.Receiver operating characteristic(ROC)curves were drawn to analyze the predictive efficacy of MHR,MPV,SD+SV4 in EH patients with LVH.Results Compared with patients without LVH,the levels of hypertension duration,BMI,systolic blood pressure,WBC,NE,monocyte,LVMI,MHR,MPV,SD+SV4 in LVH group were higher,the difference was statistically significant(P<0.05);MHR,MPV,SD+SV4 were posi⁃tively correlated with LVMI in EH patients(P<0.05).Hypertension duration,systolic blood pressure,MHR,MPV,SD+SV4 were independent risk factors for LVH in EH patients(P<0.05).The area under the curve of MHR,MPV,SD+SV4 combined detection to diagnose LVH in EH patients was 0.939,which was better than that of single detection(P<0.05).Conclusion MHR,MPV and the new ECG standard SD+SV4 are influen⁃tial factors in the development of LVH in patients with essential hypertension.The combined detection of MHR,MPV,and SD+SV4 has shown to have good predictive value for diagnosing LVH.
万方数据
维普
