The application value of ultrasonic multi?parameter imaging technology combined with serum OPG,RANKL level detection and bone mineral density evaluation in the analysis of bone metabolism status in patients with frozen shoulder
Objective To explore the bone metabolism status of frozen shoulder patients through ultrasonic multi⁃parameter imaging combined with serum OPG,RANKL level detection and bone mineral den⁃sity evaluation.Methods A total of 124 patients with frozen shoulders who were treated at Baoji High⁃tech Hospital from January 2022 to January 2024 were selected as the study subjects.Based on the results of bone mineral density measurement,they were divided into three groups:group A(normal bone mass group,n=37):T value≥-1.0,group B(osteopenia group,n=51):T value between-2.5 and-1.0;group C(osteoporosis group,n=36):T value≤-2.5.In addition,61 healthy people who underwent physical examinations in our hos⁃pital during the same period were selected as the control group.The general data,ultrasonic multi⁃parameter im⁃aging,serum OPG,RANKL and T values of the four groups were compared.The ROC curve was used to ana⁃lyze the value of ultrasonic multi⁃parameter imaging combined with serum OPG,RANKL and T values in evalu⁃ating bone metabolism in patients with frozen shoulders.Results There were no significant differences in gen⁃der,age,BMI and WHR among the four groups(P>0.05).The comparison of muscle thickness,tendon thick⁃ness,blood flow velocity,and T⁃value:Control group>Group A>Group B>Group C,with statistically sig⁃nificant differences(P<0.05).The comparison of joint capsule thickness,RI,serum OPG,and RANKL:Con⁃trol group<Group A<Group B<Group C,with statistically significant differences(P<0.05).The AUC(95%CI),sensitivity and specificity of ultrasonic multi⁃parameter imaging combined with serum OPG,RANKL and T values in evaluating bone metabolism in patients with frozen shoulder were 0.905,87.66%and 90.17%,respectively,which were significantly higher than those of ultrasonic multi⁃parameter imaging,serum OPG,RANKL and T values anlone(P<0.05).Conclusion Ultrasound multi⁃parameter imaging combined with serum OPG,RANKL and bone mineral density has high application value in evaluating the bone metabo⁃lism status of patients with frozen shoulders.This approach can not only improve the accuracy and sensitivity of diagnosis,but also provide clinicians with more comprehensive patient information.This,in turn,helps in for⁃mulating more personalized and accurate treatment plans.
OPGRANKLBone mineral densityFrozen shoulderBone metabolism