Advances in the study of intracellular survival and immune escape mechanisms of Brucella
Brucellosis is a zoonotic disease with multiple clinical manifestations caused by Brucella infection.Brucella is a parthenogenic intracellular parasite that can resist phagocytic bactericidal action,and cre⁃ate a microenvironment conducive to its survival,multiplication,and replication in host cells.It can persist for a long time within host cells,leading to chronic and persistent infection.The development of brucellosis into a chronic disease is linked to Brucella's ability to resist the host's immune response.This paper reviews the latest research progress on Brucella's intracellular parasitic mechanism and immune escape mechanism,aiming to pro⁃vide new insights for the prevention and treatment of Brucella.
万方数据
维普
