Clinical efficacy of neuroendoscopic clearance via frontal keyhole approach for hyperten-sive basal ganglia hemorrhage
Objective To explore the clinical efficacy of neuroendoscopic hematoma clearance through the frontal keyhole approach for hypertensive basal ganglia hemorrhage(HBGH).Methods From September 2022 to September 2023,65 patients with HBGH who underwent surgical treatment in our hospital were selected.Among them,31 cases were treated with traditional hematoma removal surgery(control group),and 34 cases were treated with neuroendoscopic hematoma removal surgery through the frontal key-hole approach(test group).Perioperative indicators(surgical time,intraoperative bleeding volume,hema-toma clearance rate,extubation time,hospitalization time,pupil recovery time,etc.)were compared between both groups.Peripheral cerebral edema volume,National Institutes of Health Stroke Scale(NIHSS)score,Glasgow Coma Scale(GCS)score,Glasgow Outcome Scale(GOS)grading,serum aquaporin 4(AQP4)level,and complications were analyzed between the two groups.Results The study group had a longer surgi-cal time,less intraoperative bleeding,a higher hematoma clearance rate,a shorter pupil recovery time,extu-bation time,and hospitalization time compared to the control group,and the differences were statistically sig-nificant(P<0.05).Six months after surgery,the volume of peripheral brain edema decreased in both groups,with the study group showing a lower volume,and a statistically significant difference(P<0.05).Both groups demonstrated a decrease in NIHSS scores and serum AQP4 levels,with the study group having even lower scores,and the difference was statistically significant(P<0.05).The GOS grading of the research group was better than that of the control group,and the difference was statistically significant(P<0.05).Two weeks after surgery,both groups showed an increase in GCS scores,with the study group having a higher score,and the difference was statistically significant(P<0.05).The incidence of complications in the study group was lower than that in the control group,and the difference was statistically significant(P<0.05).Conclusion Neuroen-doscopic hematoma removal surgery using the frontal keyhole approach has a positive impact on removing he-matomas,reducing brain edema,and promoting early recovery of neurological function in patients.
Hypertensive basal ganglia hemorrhageNeuroendoscopic hematoma removal surgery through the frontal keyhole approachAquaporin 4Cerebral edema
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