Epidemiological characteristics of community-acquired pneumonia pathogenesis in children at a tertiary hospital from 2019 to 2022
Objective To investigate the pathogenic characteristics of Community Acquired Pneu-monia(CAP)in children from 2019 to 2022 at the Fist Peole's Hospital of Benghu city.Methods From Janu-ary 2019 to December 2022,a study was conducted on 8,333 children with community-acquired pneumonia who were admitted to Bengbu Children's Hospital.Nasopharyngeal swabs,sputum or venous blood samples were collected from the children and tested for respiratory viruses including Flu A,Flu B,RSV,ADV,PIV1,PIV2,and PIV3,as well as bacteria and MP.The general clinical data of the children were recorded.Results The children were predominantly boys(61.27%),with the highest proportion of children aged 1-23 months at 59.33%.In winter,3,348 children were admitted to the hospital,accounting for 40.18%,which was higher than other seasons.Admissions were mainly children with non-severe and benign outcomes.The to-tal number of bacterial,viral,MP,and co-infections detected was 119(2.17%),1,394(25.44%),3,022(55.15%),and 945(17.24%),respectively.The total pathogen detection rate was 65.76%(5,480/8,333).The differences in the number of patients,total bacteria,respiratory viruses,MP and co-infections were statistically significant between years(P<0.05).Co-infections of FluA and PIV3 accounted for 31.85%and 31.53%of their own total detection rate respectively.Among the 945 cases of co-infections,392(41.48%)cases of MP co-infec-tion were the most common.901 cases of co-infections of 2 pathogens accounted for the highest percentage(95.34%),with the most common mode of co-infections being viral+MP(82.12%).The number of PIV1,PIV2,PIV3,Flu A,RSV,bacterial,and co-infections detected was significantly higher in children aged 1 to 23 months than that in children aged 2～4 years and≥5 years,and the difference was statistically significant(P<0.05).MP was detected in children≥5 years of age more than in other age groups,and the difference was statistically signifi-cant(P<0.05).Flu B and ADV did not show statistically significant differences in detection among each age group(P>0.05).MP,PIV1,PIV2,PIV3 were most detected in the fall,while Flu A,Flu B,RSV and bacteria were most detected in the winter.Conclusion In clinical practice,it is important to be aware of differences in the detectability of pathogens across ages and seasons,and be mindful of co-infections involving multiple pathogens.
Community-acquired pneumonia in childrenEtiologyEpidemiological features
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