This study focused on the construction defects of elevator shafts,and a 10-story seismic isolation structure was simulated and established using software SAP2000.Three different scenarios were investigated regarding the different fillings around the elevator shaft,the different distances between the elevator shaft and the fillings,and the different positions of the elevator shaft,with the aim of studying the collision risk.The results of the time-history analysis indicate that the influence of stiffness on the bottom acceleration of the building could be larger,while its effect on the top acceleration,inter-story displacement,and inter-story shear force is relatively small but larger compared to the response of the un-collided structure.Additionally,the collision spacing was also related to seismic characteristics.Furthermore,when the elevator shaft was located on the outer side of the building,a noticeable twisting effect occurred,further increasing the response of the structure.Therefore,it can be concluded that the construction defects of elevator shafts can seriously affect the vibration reduction effect of seismic isolation structures.