The application prospect of high-rise base-isolated structures in high-intensity cities of China is broad,and it is necessary and pressing to study on the seismic response of this high-rise base-isolated structures.Taking a real office building as a prototype,shaking table tests for its one-fifteen scale model were conducted.Its dynamic characteristics and dynamic responses under different earthquakes were measured.By inputting different seismic waves,the dynamic characteristics,acceleration response,displacement response and isolated layer response of the model were obtained,and the special sudden amplification phenomenon at the upper part of the structure was analyzed.The results indicate that the high-rise base-isolated structure has good overall energy dissipation and seismic performance.The structure may have high-order effects due to the fact that the natural frequency of some high-rise structure is the same as a certain high-order frequency of the whole structure,and the high-order effects may become increasingly strong due to the similarity between the natural frequency of this high-rise structure and the dominant frequency of the site.The high-order effect causes the upper structure of the isolation layer to suddenly change beyond the elastic-plastic interlayer displacement angle under rare earthquake actions,while exacerbating the uplift and sway effects,causing the isolation support to exceed the tensile limit.Therefore,vibration control measures must be taken to suppress the higher order effect.