Objective To investigate the prevalence of cognitive impairment in the elderly aged≥60 years in Guangzhou,and analyze the related influencing factors.Methods From January to December 2023,3 districts of Guang-zhou were selected by multi-stage cluster random sampling method,and 8 community health service centers in each dis-trict were selected as survey sites.The elderly people aged ≥60 years old were selected from the survey sites to conduct cog-nitive function assessment and questionnaire survey.The descriptive epidemiological analysis was used to analyze the prevalence of cognitive impairment in the elderly,and univariate and multivariate logistic analyses were used to analyze the influencing factors.Results A total of 2 420 elderly residents in Guangzhou were surveyed using an effective question-naire,with males accounting for 43.35%and females accounting for 56.65%.The age range was mainly from 60 to 79 years old,accounting for 87.02%.The education level was mainly below high school,accounting for 85.62%.There were 292 el-derly people assessed as cognitive impairment,accounting for 12.07%.Multivariate logistic regression analysis showed that ≥70 years old(OR=1.665,3.471),per capita monthly family income<3 000 yuan(OR=1.859),drinking(OR=1.690),combined use of different types of drugs(OR=2.661)were risk factors affecting cognitive impairment in elderly aged ≥60 years.Education level of junior high school or above(OR=0.268,0.372)and high socio-economic status(OR=0.324)was a protective factor.Conclusions The prevalence of cognitive impairment in the elderly aged ≥60 years in Guangzhou was high.Advanced age,drinking,low and education level socio-economic status,and combined use of differ-ent types of drugs are risk factors affecting cognitive impairment.