Objective To analyze the epidemiological characteristics and spatiotemporal distribution features of dengue fever in Shantou City from 2011 to 2020,to provide a reference basis for formulating precise prevention and control strategies.Methods Data on dengue fever outbreaks in Shantou City from 2011 to 2020 were collected.Descriptive epide-miology,spatial autocorrelation analysis,and spatiotemporal scan statistic were used to analyze the patterns of dengue fe-ver.Results From 2011 to 2020,a total of 1 271 cases of dengue fever were reported in Shantou City,with an average an-nual incidence rate of 2.23/100 000.Among them,there were 1 153 local cases(90.72%).Dengue fever cases were re-ported in all seven districts of Shantou City,and the number of local cases was positively correlated with the number of im-ported cases(rs=0.83,P<0.05).The results of spatial autocorrelation analysis indicated that the local cases showed signifi-cant spatial clustering in 2014 and 2019,16"hot spot"areas were identified,with no"cold spot"areas in the city.A total of four local case cluster areas were detected by spatiotemporal scanning:the first type of cluster area involving 17 streets(towns)in Jinping District and Longhu District,with the clustering period from July to September 2019;the other three cluster areas were distributed in Chaonan District(two)and Chaoyang District(one).Conclusions The dengue fe-ver epidemic in Shantou City has obvious spatiotemporal clustering characteristics,with a correlation between local cases and imported cases in terms of spatial and temporal clustering.Targeted prevention and control measures should be taken before the epidemic season and in high-incidence streets(towns).