A new,green and extra additive-free synthesis method of alkyl thioesters in water media was developed in this paper.By using alkyl halides and thioamide as the raw materials,the reaction can proceed smoothly in aqueous phase for 4 h,to afford the target thioester products with high yields,and the method can be compatible with various functional groups.Compared with the available methods,this method has the advantages of simple experimental operation,green and high efficiency,good atomic economy,and can easily be scaled up in gram scale,and has high practical application value.
维普
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