Piezoelectric Effect of Polyether Ether Ketone Fibers Loaded with Bismuth Oxide Stimulating Osteogenic Differentiation
Oxygen-vacancy bismuth oxide(BiO2‒x)with excellent piezoelectric property was prepared by ultrasonic peel method and loaded on polyether ether ketone(PEEK)fiber by using chlorogenic acid.A kind of rotator cuff patch material with piezoelectric effect was designed,and its effects on macrophage polarization and osteoblast behavior were studied.The results showed that after loading BiO2‒x,not only the surface properties(roughness,hydrophilicity,and surface energy,etc.)of PEEK fibers were obviously improved,but also the piezoelectric proper-ties were significantly enhanced(piezoelectric coefficient of 3.8 pC/N,output voltage of 0.97 V and output current of 575.6 μA).The patch material not only promoted the anti-inflammatory M2 macrophage polarization,but also promoted the adhesion,proliferation,and osteogenic differentiation of osteoblasts.The patch material has potential application for repairing rotator cuff tear.
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