Near-infrared Emissive 1,2-Dioxetane-based Chemiluminescent Probes

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外文摘要：Chemiluminescence,a phenomenon emitting light from chemical reactions rather than photon absorption,has gained significant interest for applications in bioimaging and biosensing due to its high sensitivity and low background interference.Now there is a growing interest in near-infrared(NIR)chemiluminescent probes for improved tissue penetration and reduced autofluorescence.This review summarizes NIR emissive chemiluminescent probes based on 1,2-dioxetane and discusses their chemical structures and applications.Structure modification strategies for red-shifting wavelength and enhancing brightness include incorporating electron-withdrawing groups,designing chemiluminophore-fluorophore cassettes,and exploring alternative chemiluminescent scaffolds.This review aims to inspire the exploration of NIR chemiluminescent probes in disease detection and treatment.

外文关键词：

ChemiluminescenceNear-infraredDioxetaneBioimagingBiosensing

作者：

CHEN Yingqi、BUDIANTA Richard、NING Yingying

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作者单位：

Spin-X Institute,School of Chemistry and Chemical Engineering,School of Biomedical Sciences and Engineering,State Key Laboratory of Luminescent Materials and Devices,Guangdong-Hong Kong-Macao Joint Laboratory of Optoelectronic and Magnetic Functional Materials,South China University of Technology,Guangzhou 510641,P.R.China

基金：

National Natural Science Foundation of ChinaOpen Funds of the State Key Laboratory of Chemo/Bio-Sensing and Chemometrics,Hunan University,ChinaProgram of Guangdong Basic Research Center of Excellence for Functional Molecular Engineering,China

项目编号：

2237107720240619

出版年：

2024

DOI：

10.1007/s40242-024-4166-6

高等学校化学研究(英文版)

吉林大学

高等学校化学研究(英文版)

CSTPCD

影响因子：0.871

ISSN：1005-9040

年,卷(期)：2024.40(5)