Evaluation of the consciousness state index based on auditory evoked potentials for monitoring anesthetic depth in surgeries for patients with high-level paraplegia
Objective To evaluate the efficacy of the consciousness state index(CSI)based on auditory evoked potentials(AEP)for monitoring anesthetic depth during surgeries for patients with high-level paraplegia.Methods Thirty patients undergoing anesthesia for high-level paraplegia surgery at Chinese Medicine Hospital of Gaozhou City from April 2022 to February 2024 were enrolled and randomly divided into a study group(Group A)and a control group(Group C),with 15 patients in each group.CSI monitoring was used in both groups.Anesthesia depth in Group C was adjusted based on the anesthesiologist's clinical judgment,while Group A adjusted anesthetic dosages based on CSI read-ings.Parameters including electrocardiogram(ECG),mean arterial pressure(MAP),heart rate(HR),oxygen satura-tion(SpO2),and CSI were recorded at various time points:10 minutes after entering the operating room(T0),intubation(T1),skin incision(T2),surgical exploration(T3),end of surgery(T4),recovery of consciousness(T5),and just before leaving the operating room(T6).Awakening time,intraoperative complications,and adverse reactions(delayed recovery,nausea,vomiting,agitation,coughing,intraoperative awareness,and postoperative cognitive impairment)were compared between the two groups.Results No significant differences were found in MAP,HR,or SpO2 between Groups A and C at T0 and T1(P>0.05).However,at T2,T3,T4,T5,and T6,Group A exhibited more stable vital signs,with significantly smaller fluctuations compared to Group C(P<0.05).The CSI values at T0 were similar in both groups(P>0.05),but were significantly higher in Group A than Group C at T1,T2,T3,T4,T5,and T6(P<0.05).Group A showed shorter awakening times and lower incidences of intraoperative hypotension and awareness compared to Group C(P<0.05).Conclusion Monitoring anesthetic depth using CSI based on AEP offers significant advantages for anesthe-sia management in surgeries for high-level paraplegia.This approach stabilizes vital signs,reduces adverse reactions and intraoperative awareness,and enhances anesthesia safety,making it a valuable clinical choice.
auditory evoked potentialelectrocardiogramcerebral state indexhigh paraplegia