Research progress on diabetic nephropathy complicated with pregnancy
The number of pregnant women with gestational diabetes has been steadily increasing worldwide.These pregnancies have elevated risk of various complications,including miscarriage,congenital abnormalities,macrosomia,fetal growth restriction,preeclampsia,preterm birth,and stillbirth.For pregnant women with diabetic nephropathy,it is crucial to assess the impact of pregnancy on kidney function and the influence of kidney disease on pregnancy outcomes.Pregnant women with normal kidney function and microalbuminuria have lower risk of kidney function loss during pregnancy,whereas those with a glomerular filtration rate<60 ml/min and/or proteinuria ≥3 g/24 h in early pregnancy face risk of permanent kidney damage.The risk of complications for both the fetuses and mothers is associated with the severity of chronic kidney disease and glycemic control.Advancements in prenatal care have improved outcomes for both the fetuses and mothers.Preconception counseling has become a critical factor for the successful pregnancy of all diabetic women,especially those with diabetes and chronic kidney disease.
Diabetic nephropathyChronic kidney diseasePregnant womenPrenatal care