Effect of troponin T level on prolonged mechanical ventilation in infants after cardiac surgery
Objective To explore the effect of troponin T on prolonged mechanical ventilation in infants after cardiac surgery.Methods One hundred and ninety-two infants with congenital heart disease who underwent cardiac surgery under cardiopulmonary bypass in Department of Cardiac Surgery,Guangdong Provincial People's Hospital,Southern Medical University from January to April 2019 were retrospectively selected as the study objects.According to the immediate troponin T level after surgery,they were divided into a high-value group(3 798.0-10 000.0 ng/L),a middle-value group(1 827.0-3 709.0 ng/L),and a low-value group(316.2-1 801.0 ng/L),with 64 cases in each group.There were 28 girls and 36 boys in the low-value group;they were 203.00(129.75,274.50)days old.There were 30 girls and 34 boys in the middle-value group;they were 118.00(16.50,173.75)days old.There were 24 girls and 40 boys in the high-value group;they were 168.50(78.00,219.25)days old.The analysis of variance,rank sum test,and x2 test were used for the statistical analysis.The univariate and multivariate logistic regression models were used to analyze the correlation between postoperative troponin T level and prolonged mechanical ventilation.The univariate and multivariate linear regression models were used to analyze the correlation between postoperative troponin T level on one hand and length of stay in the intensive care unit and hospitalization time after the operation on the other hand.Results The younger the infants were and the longer the extracorporeal circulation during surgery and the aortic cross-clamp time were,the higher the postoperative troponin T level was(all P＜0.05).After adjusting the gender,days,gestational age,preoperative hemoglobin,preoperative serum creatinine,cardiopulmonary bypass time,aortic cross-clamp time,and RACHS-1 score,the multivariate regression model found that the elevated troponin T level was an independent risk factor for prolonged mechanical ventilation[OR=1.2(1.1,1.3),P＜0.001].Conclusion The elevation of troponin T level is associated with prolonged postoperative mechanical ventilation after congenital heart surgery in infants.
InfantsCongenital heart diseaseTroponin TMechanical ventilation timeCardiac surgery
万方数据
维普
