Progress of dexmedetomidine for intrathecal injection
In order to improve the quality of anesthesia,reduce the amount of intrathecal local anesthetics,and decrease the incidence of adverse reactions,the application of intrathecal local anesthetics and intrathecal adjuvant drugs has received more and more attention.Dexmedetomidine,as a kind of highly selective,specific,and potent α2-adrenergic agonist,has been a hotspot drug in research.Its analgesic effects have been proved in a variety of surgeries,but the analgesic mechanism of its intrathecal application and the issue of safety are still difficult problems in the clinical research.In order to better improve the quality of anesthesia and promote the advancement of the medical cause,the review on the progress of the research on the use of dexmedetomidine for intrathecal injection is described.