Susceptibility weighted angiography in evaluation of ischemic penumbra in patients with acute ischemic stroke
Objective To analyze the clinical value of susceptibility weighted angiography(SWAN)in evaluating the location and range of ischemic penumbra(IP)in patients with acute ischemic stroke.Methods Twenty-five patients with acute ischemic stroke who underwent magnetic resonance imaging examination at Lianyungang Hospital,Nanjing University of Chinese Medicine from January 2019 to December 2022 were selected,including 15 males and 10 females who were(55.7±14.4)years old.The diffusion weighted imaging(DWI),T2 weighted liquid attenuation inversion recovery sequence(T2 Flair),SWAN,and three-dimensional arterial spin labeling(3D ASL)sequences were performed on all the patients.The high signal area displayed on DWI and the low signal area displayed on the apparent diffusion coefficient(ADC)map were determined as the infarct core area.The SWAN sequence was analyzed to indicate the positive area of prominent vascular sign(PVS).The 3D ASL sequence indicates differences in the mismatch range between the low perfusion area of cerebral blood flow(CBF)and the infarct core interval.The independent-sample t test was applied.Results The mismatch range of SWAN-DWI was(2 289.42± 721.47)mm2,and that of 3D ASL-DWI was(2 331.59±730.71)mm2,with no statistical difference between the two(t=0.205,P=0.838).Conclusion PVS prompted by magnetic resonance SWAN sequence can be used to evaluate the location and range of IP,and provide image basis for the selection of clinical treatment.