Adenosarcoma of uterus is considered to be a low grade malignant uterine tumor.It has a low incidence and lacks specific clinical manifestations and laboratory and radiographic examinations.Most patients with adenosarcoma of uterus have good prognosis.This paper reports the diagnosis and treatment of a patient with refractory adenosarcoma of uterus who had metastasis rapidly and died after surgery,so as to improve the clinicians'understanding about this disease and take individualized treatment.