Inflammatory bowel disease(IBD)is a chronic intestinal inflammatory disease caused by a variety of causes.In recent years,with the deepening of research,intestinal immune factors have gradually been paid attention to by clinical and researchers,providing an emerging research direction for IBD.We have traced related literature researches in the domestic and foreign medical databases such as PubMed/Medline/Cochrane/SinoMed/CNKI/Wanfang/CQVIP in the past 20 years,and summarize the mechanisms of intestinal nutrition,intestinal microenvironment,intestinal oxygen supply,intestinal immune factors,and circadian rhythm involved in the pathogenesis of IBD,in order to explore new therapeutic targets and lay a foundation for further study of IBD.
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