In recent years,bloodstream infection(BSI)caused by Klebsiella pneumoniae(Kp)in intensive care unit(ICU)has attracted attention in recent years due to an alarming rise in morbidity and mortality.With the increasing number of Kp-BSI patients and the development of studies,the characteristics of Kp-BSI in ICU have been further explored in clinical practice.Moreover,with the development of metagenomic Next Generation Sequencing technology,droplet digital PCR,machine learning,and other novel etiological diagnostic technologies,a new horizon has been opened for the etiological diagnosis of Kp-BSI in ICU.At the same time,the development of new antibiotics and the improvement of various therapeutic measures are expected to reduce the mortality of Kp-BSI patients in ICU.This article reviews the occurrence characteristics of ICU-Kp-BSI,its new diagnosis and treatment methods,and looks forward to the future research direction,so that we can provide some new ideas for clinical diagnosis and treatment of ICU-Kp-BSI in the future.
关键词
肺炎克雷伯菌/血流感染/医院获得性/重症监护室/进展
Key words
Klebsiella pneumoniae/Bloodstream infection/Hospital-acquired/Intensive care unit/Progress