Research progress on the characteristics and new diagnostic and treatment strategies of Klebsiella pneumoniae bloodstream infection in ICU patients
In recent years,bloodstream infection(BSI)caused by Klebsiella pneumoniae(Kp)in intensive care unit(ICU)has attracted attention in recent years due to an alarming rise in morbidity and mortality.With the increasing number of Kp-BSI patients and the development of studies,the characteristics of Kp-BSI in ICU have been further explored in clinical practice.Moreover,with the development of metagenomic Next Generation Sequencing technology,droplet digital PCR,machine learning,and other novel etiological diagnostic technologies,a new horizon has been opened for the etiological diagnosis of Kp-BSI in ICU.At the same time,the development of new antibiotics and the improvement of various therapeutic measures are expected to reduce the mortality of Kp-BSI patients in ICU.This article reviews the occurrence characteristics of ICU-Kp-BSI,its new diagnosis and treatment methods,and looks forward to the future research direction,so that we can provide some new ideas for clinical diagnosis and treatment of ICU-Kp-BSI in the future.
Klebsiella pneumoniaeBloodstream infectionHospital-acquiredIntensive care unitProgress
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