首页|结局引导的双心服务在冠心病不稳定型心绞痛患者PCI围手术期中的应用

结局引导的双心服务在冠心病不稳定型心绞痛患者PCI围手术期中的应用

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目的 探讨结局引导的双心服务在冠心病不稳定型心绞痛(UAP)患者经皮冠状动脉介入术(PCI)围手术期中的应用效果。方法 本研究为随机对照试验。选取2020年10月至2022年2月无锡市第二人民医院收治的行PCI治疗的100例UAP患者作为研究对象,随机分为对照组和研究组,各50例。研究组年龄(53。68±7。22)岁;男性31例、女性19例;体质量指数(BMI)(24。28±3。12)kg/m2;病程(3。02±0。61)年;纽约心脏病协会(NYHA)分级:Ⅰ级21例、Ⅱ级15例、Ⅲ级14例;冠状动脉病变支数:单支17例、双支20例、三支及以上13例。对照组年龄(55。32±5。76)岁;男性28例、女性22例;BMI(23。89±3。18)kg/m2;病程(2。89±0。57)年;NYHA分级:Ⅰ级23例、Ⅱ级15例、Ⅲ级12例;冠状动脉病变支数:单支15例、双支23例、三支及以上12例。对照组在围手术期采取常规护理模式,研究组在对照组的基础上采取结局引导的双心服务模式,两组均干预至患者出院。比较两组患者的干预前后焦虑抑郁情绪、心功能指标[左心室射血分数(LVEF)、B型钠尿肽(BNP)]、并发症以及西雅图心绞痛调查量表(SAQ)评分。计量资料采用t检验,计数资料采用x2检验或Fisher确切概率法,等级资料采用秩和检验。结果 干预后,研究组焦虑自评量表(SAS)评分(38。74±7。13)分、抑郁自评量表(SDS)评分(42。26±8。03)分,均低于对照组的(42。38±7。54)分、(47。78±8。12)分(t=2。480、3。418,P=0。015、0。001)。干预后,研究组LVEF为(69。33±6。89)%,高于对照组的(58。93±6。42)%(t=7。809,P<0。001);干预后,研究组BNP为(116。82±14。25)ng/L,低于对照组的(138。75±12。46)ng/L(t=8。192,P<0。001)。研究组的并发症发生率低于对照组[6。00%(3/50)比22。00%(11/50)](x2=4。070,P=0。044)。干预后,研究组SAQ的躯体活动受限程度评分(79。63±8。76)分、心绞痛稳定状态评分(57。76±9。32)分、心绞痛发作情况评分(70。37±7。11)分、治疗满意程度评分(82。23±8。04)分、疾病认知程度评分(70。12±9。07)分,均高于对照组(67。12±8。07)分、(53。35±8。22)分、(63。18±8。02)分、(69。35±9。33)分、(54。62±8。74)分(t=7。427、2。509、4。744、7。395、8。701,均P<0。05)。结论 在UAP患者PCI围手术期实施结局引导的双心服务减轻了患者的焦虑抑郁情绪,改善了患者的心功能,减少了并发症的发生,缓解了临床症状,提高了生活质量,促进患者预后改善。
Application of outcome guided bicardiac service in patients with unstable angina pectoris of coronary heart disease during the perioperative period of PCI
Objective To investigate the application effect of outcome guided bicardiac service in the perioperative period of percutaneous coronary intervention(PCI)for patients with unstable angina pectoris(UAP).Methods It was a randomized controlled trial.A total of 100 patients with UAP undergoing PCI in Wuxi Second People's Hospital from October 2020 to February 2022 were randomly divided into a control group and a study group,with 50 cases in each group.The age of the study group was(53.68±7.22)years old;there were 31 males and 19 females;the body mass index(BMI)was(24.28±3.12)kg/m2;the course of disease was(3.02±0.61)years;the New York Heart Association(NYHA)classification was grade Ⅰ in 21 cases,grade Ⅱ in 15 cases,and grade Ⅲ in 14 cases;the number of coronary artery lesions was single vessel in 17 cases,double vessels in 20 cases,and three or more vessels in 13 cases.The control group was(55.32±5.76)years old;there were 28 males and 22 females;the BMI was(23.89±3.18)kg/m2;the course of disease was(2.89±0.57)years;the NYHA classification was grade Ⅰ in 23 cases,grade Ⅱ in 15 cases,and gradeⅢ in 12 cases;the number of coronary artery lesions was single vessel in 15 cases,double vessels in 23 cases,and three or more vessels in 12 cases.The control group received the routine nursing mode during the perioperative period,and the study group received the outcome guided bicardiac service mode on the basis of the control group.Both groups were intervened till discharge.The anxiety and depression,cardiac function indexes[left ventricular ejection fraction(LVEF)and B-type natriuretic peptide(BNP)],complications,and Seattle Angina Questionnaire(SAQ)scores of the two groups were compared before and after intervention.t test was used for the measurement data,x2 test or Fisher exact probability method for the count data,and rank sum test for the rank data.Results After intervention,the scores of Self-rating Anxiety Scale(SAS)[(38.74±7.13)points]and Self-rating Depression Scale(SDS)[(42.26±8.03)points]of the study group were lower than those of the control group[(42.38±7.54)and(47.78±8.12)points](t=2.480 and 3.418,P=0.015 and 0.001).After intervention,the LVEF of the study group was(69.33±6.89)%,which was higher than that of the control group[(58.93±6.42)%](t=7.809,P<0.001);the BNP in the study group was(116.82± 14.25)ng/L,which was lower than that in the control group[(138.75±12.46)ng/L](t=8.192,P<0.001).The incidence of complications in the study group was lower than that in the control group[6.00%(3/50)vs.22.00%(11/50)](x2=4.070,P=0.044).After intervention,the scores of physical activity restriction[(79.63±8.76)points],angina stable state[(57.76±9.32)points],angina pectoris attack[(70.37±7.11)points],treatment satisfaction[(82.23±8.04)points],and disease cognition[(70.12±9.07)points]of the SAQ in the study group were higher than those in the control group[(67.12±8.07)points,(53.35±8.22)points,(63.18±8.02)points,(69.35±9.33)points,and(54.62± 8.74)points](t=7.427,2.509,4.744,7.395,and 8.701;all P<0.05).Conclusion The implementation of outcome guided bicardiac service in the perioperative period of PCI for UAP patients can reduce the patients'anxiety and depression,improve their cardiac function,reduce the occurrence of complications,alleviate the clinical symptoms,improve the quality of life,and promote the prognosis.

Coronary heart diseaseUnstable angina pectorisPercutaneous coronary interventionAnxietyDepressionCardiac functionOutcome guidedBicardiac service

张展、李杏、莫琳勤、苏严琳、孙艳彬

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无锡市第二人民医院心内科,无锡 214000

冠心病 不稳定型心绞痛 经皮冠状动脉介入术 焦虑 抑郁 心功能 结局引导 双心服务

国家自然科学基金

81800283

2024

国际医药卫生导报
中华医学会,国际医药卫生导报社

国际医药卫生导报

影响因子:0.781
ISSN:1007-1245
年,卷(期):2024.30(4)
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