Contrast-enhanced CT combined with contrast-enhanced ultrasound in evaluation of efficacy of TACE for patients with hepatocellular carcinoma
Objective To investigate the value of contrast-enhanced computed tomography(CECT)combined with contrast-enhanced ultrasound(CEUS)in the evaluation of the efficacy of transcatheter arterial chemoembolization(TACE)for patients with hepatocellular carcinoma(HCC).Methods The clinical data of 96 patients with HCC who underwent TACE in Liaocheng People's Hospital were analyzed retrospectively.Among the 96 patients,there were 53 males and 43 females;they were(52.69±4.08)old.The Child-pugh classification results showed that there were 49 cases of grade A and 47 cases of grade B.All the patients received CECT,CEUS,and digital subtraction angiography(DSA)examinations 1 month after surgery.The DSA results were taken as the golden standard to evaluate the diagnostic performance of CEUS,CECT,and CEUS combined with CECT for residual tumors.The Kappa test was used for consistency analysis,and the imaging findings of residual lesions were observed.Results One month after TACE,DSA found 15 cases of residual tumors,accounting for 15.63%.CEUS diagnosed 11 cases(11.46%)of residual tumors;CECT diagnosed 10 cases(10.42%)of residual tumors;CEUS combined with CECT diagnosed 13 cases(13.54%)of residual tumors.The diagnostic sensitivity,specificity,accuracy,negative predictive value,positive predictive value,and Kappa value of CEUS combined with CECT(80.00%,98.77%,95.83%,96.39%,92.31%,and 0.833)were higher than those of CEUS and CECT.Conclusions The combination of CECT and CEUS has significant advantages in evaluating the efficacy of TACE for patients with HCC.It can be used as an effective method for evaluating the efficacy after TACE.