Effects of different ball holding methods for patients with hepatocellular carcinoma who are treated by chemotherapy and take PICC
Objective To explore the effects of different ball holding methods on axillary vein blood flow velocity,catheter-related thrombosis(CRT)prevention,and exercise fatigue in patients with hepatocellular carcinoma who are treated by chemotherapy and take peripherally inserted central catheter(PICC).Methods One hundred and five patients with hepatocellular carcinoma who were treated by chemotherapy and took PICC at First Hospital,Henan University of Science and Technology from October 2020 to November 2022 were retrospectively selected as the study objects,and were divided into a routine group(52 cases)and a regular group(53 cases)according to the ball holding methods.There were 27 males and 25 females in the routine group;they were(51.77±11.71)years old.There were 29 males and 24 females in the regular group;they were(52.13±12.28)years old.The routine group held the ball for about 500 times in three times every day.The regular group held the ball 25-30 times after the meals every day,and gripped it tightly for 10 s and released it 10 s each time;the grip strength was determined by squeezing the grip ball to 1/2.The axillary vein blood flow velocities,incidences of CRT,mechanical phlebitis,and catheter displacement,and exercise fatigue were compared between the two groups.t test,Fisher's exact test,and rank sum test were used.Results Four weeks after catheter insertion,the maximum velocity of axillary vein and the velocity of axillary vein per unit time in the regular group were higher than those in the conventional group[(14.61±2.03)cm/s vs.(11.56±1.32)cm/s and(9.13± 1.67)cm/s vs.(6.57±0.92)cm/s;t=9.1083 and 9.7030;both P＜0.05].There were no statistical differences in the incidences of CRT,mechanical phlebitis,and catheter displacement between the regular group and the routine group[1.89％(1/53)vs.5.77％(3/52),0 vs.3.85％(2/52),and 0 vs.1.92％(1/52);P=0.362 9,0.242 9,and 0.495 2].The exercise fatigue level during 12 days'catheter insertion in the regular group was better than that in the routine group(Z=2.574 7,P=0.005 0).Conclusion Regular ball holding can improve the exercise fatigue of patients with hepatocellular carcinoma who are treated by chemotherapy and take PICC,adjust the axillary vein blood flow velocity,and reduce the incidences of CRT,mechanical phlebitis,and catheter displacement.
万方数据
维普
