Effect of spinal-epidural anesthesia for parturients taking painless delivery
Objective To analyze the effect of spinal-epidural anesthesia for parturients taking painless delivery.Methods A prospective study was conducted on 302 parturients who were admitted to Baoji Maternal and Child Health Hospital for painless delivery from June 2021 to June 2023.They were divided into a control group and a research group by the random number table method,with 151 cases in each group.The control group were(28.69±3.77)years old and(39.14±1.15)weeks pregnant,and took epidural anesthesia.The research group were(28.72± 3.81)years old and(39.16±1.10)weeks pregnant,and took spinal-epidural anesthesia.The delivery-related indicators,stress indicators,and delivery outcomes were compared between the two groups.t and x2 tests were applied.Results Compared with those in the control group,the first and second stages of labor,the total stage of labor,the onset time of anesthesia,the recovery time of intestinal peristalsis,and the hospitalization time in the research group were shorter,the bleeding volume 2 hours after delivery in the research group was lower,and the duration of anesthesia in the research group was longer;there were statistical differences(all P＜0.05).The scores of the Visual Analogue Scale(VAS)in the second and third stages of labor and when the cervix was fully open and the Bro-mage score of the parturient after successful delivery in the research group were lower than those in the control group;the score of milk yield 24 h after delivery in the research group was higher than that in the control group;there were statistical differences(all P＜0.05).Twenty-four hours after delivery,the serum levels of cortisol(COR)[(33.66±4.53)mg/L and(18.44±3.61)mg/L],norepinephrine(NE)[(158.16±16.54)ng/L and(142.35±15.48)ng/L],prostaglandin E2(PGE2)[(99.36±8.62)ng/L and(90.12±8.47)ng/L],substance P(SP)[(4.12±0.58)mg/L and(3.47± 0.45)mg/L],and prolactin(PRL)[(245.63±24.12)μg/L and(276.30±25.78)μg/L]in the control group and the research group were higher than those before delivery,the changes of serum COR,NE,PGE2,SP,and PRL of the research group were more obvious(t=32.288,20.106,9.395,10.880,and 10.675;all P＜0.001).There were no statistical differences in the delivery outcomes between the two groups(all P＞0.05).Conclusion The application of spinal-epidural anesthesia in parturients taking painless delivery can shorten the labor stages,reduce the expression of stress indicators and pain-causing factors,relieve their pain,and improve their lactation function,and have good delivery outcomes.
Spinal-epidural anesthesiaPainless deliveryPain-causing factorsLactation function
万方数据
维普
