Clinical characteristics and prognosis of patients with staphylococcal-associated pyogenic spondylitis
Objective To explore the pathological changes of staphylococcal-associated pyogenic spondylitis(PS)based on laboratory examination,clinical characteristics,and prognosis,and to provide references for its clinical diagnosis and treatment.Methods Eighty patients with staphylococcus-associated PS admitted to Jinan Eighth People's Hospital from January 2012 to October 2022 were selected.Their basic information,lesion segment distribution,laboratory indicators,CT and MRI imaging features and prognosis were statistically analyzed.Results Among the 80 patients were statistically analyzed,there were 36 males and 44 females;63 cases ≥50 years old;all of them had low back pain in some degree;their score of Visual Analogue Scale(VAS)was(7.38±0.23).The lesion segments were mainly distributed in T8-T9(15 cases,18.75％),L3-L4(12 cases,15.00％),and L2-L3(10 cases,12.50％).Platelets,erythrocyte sedimentation rate,white blood cell count,neutrophils,ferritin,and C-reactive protein increased,while serum hemoglobin and albumin decreased.The CT examination showed that PS lesions damaged the vertebral bone and surrounding soft tissue swelled.The CT enhanced scan showed no enhancement in the central liquefaction necrosis area,and the edge of the paraspinal soft tissue was enhanced.The MRI examination showed abnormal signal foci in the lesion vertebral body,swelling in the paraspinal soft tissue,abnormal signal foci in the disc destruction area,which showed low signal on T1WI and high signal on T2WI with fat compression.The MRI enhanced scan showed significant enhancement,and T2WI showed high signal with fat compression.After systematic treatment,all the patients showed a significant decrease in VAS score[(2.41±0.17)],and had good prognosis.Conclusion PS caused by staphylococcus is accompanied by varying degrees of low back pain,with the main affected segments being T8,T9,L3,and L4.CT,MRI,C-reactive protein,and erythrocyte sedimentation rate elevation can be used as effective auxiliary tests for the diagnosis of PS.Timely relevant treatments can effectively alleviate the patients'pain and achieve cured effect.
万方数据
维普
