Effect of dietary support at night on TIPS for patients with chronic acute liver failure
Objective To investigate the effects of dietary support at night on liver reserve function,anthropometric indicators,and protein levels in patients with chronic acute liver failure treated by transjugular intrahepatic portal vein shunt(TIPS).Methods A total of 107 patients with chronic acute liver failure who received TIPS in First Hospital,Henan University of Science and Technology from September 2020 to September 2022 were selected for the prospective study,and were divided into a control group(53 cases)and a study group(54 cases)by the simple randomization method.There were 42 males and 11 females in the control group;they were 27-69(53.15±4.79)years old.There were 45 males and 9 females in the study group;they were 24-67(52.48±5.02)years old.The control group received daily dietary support treatment;in addition,the study group took night meal nutritional support.Both groups were treated for 2 months.t test was used.Results The scores of the nutrition risk screening(NRS-2002)and Child-Pugh 1 month after the treatment in the study group were lower than those in the control group[(2.43±0.47)vs.(3.68± 0.91)and(7.12±1.41)vs.(8.64±1.63)],with statistical differences(t=8.90 and 5.16;both P＜0.05).One month after the treatment,the body mass index(BMI),upper arm muscle circumference(MAMC),and triceps skin fold thickness(TSF)in the study group were higher than those in the control group[(22.11±1.83)kg/m2 vs.(21.09±2.05)kg/m2,(24.18±2.35)cm vs.(22.48±3.02)cm,and(13.06±3.31)cm vs.(11.26±2.78)cm],with statistical differences(t=2.71,3.25,and 3.05;all P＜0.05).One month after the treatment,the levels of albumin(ALB),prealbumin(PA),and transferrin(TRF)in the study group were higher than those in the control group[(34.06±7.24)g/L vs.(31.26± 6.71)g/L,(138.26±33.49)mg/L vs.(103.18±24.36)mg/L,and(1 887.14±241.59)mg/L vs.(1 695.26± 216.31)mg/L],with statistical differences(t=2.08,6.21,and 4.33;all P＜0.05).Conclusion Adding nutritional support therapy with night meal can reduce the risk of malnutrition in patients with chronic acute liver failure after TIPS,enhance their liver reserve function,and improve their physical and nutritional status.
Chronic plus acute liver failureTransjugular intrahepatic portal vein shuntNutritional support with extra meals at nightLiver reserve functionNutritional risk
万方数据
维普
