Clinical value of 3D-CTBA precise localization in patients undergoing thoracoscopic segmentectomy for early NSCLC
Objective To investigate the effect of three-dimensional computed tomography bronchography and angiography(3D-CTBA)precise localization on the improvement of carbohydrate antigen 125(CA125),carbohydrate antigen 724(CA724),carcinoembryonic antigen(CEA),and lung function in patients with thoracoscopic segmentectomy.Methods A total of 135 patients with early non-small cell lung cancer(NSCLC)who underwent thoracoscopic segmentectomy in Anyang Hospital of Traditional Chinese Medicine from August 2019 to August 2022 were prospectively selected and were divided into a control group(67 cases)and a study group(68 cases)by the random number table method.In the control group,there were 42 males and 25 females,aged(58.75±6.81)years,with a tumor diameter of(1.39±0.25)cm;in the study group,there were 41 males and 27 females,aged(58.22±6.35)years,with a tumor diameter of(1.36±0.31)cm.The control group underwent thoracoscopic segmentectomy,while the study group underwent 3D-CTBA precise localization before thoracoscopic segmentectomy.The operation-related indexes,serum tumor marker levels before and 7 days after surgery,changes in pulmonary function indexes before and 1 month after surgery,and incidence of complications were compared between the two groups.x2 test and independent sample t test were used.Results The operation time and thoracic drainage tube removal time[(115.77±7.96)min and(3.48±0.81)d]in the study group were shorter than those in the control group[(140.05±8.77)min and(4.52±0.74)d],the intraoperative blood loss and postoperative drainage volume were less than those in the control group[(129.83±11.65)ml vs.(150.02±10.23)ml,(541.23±41.78)ml vs.(720.22±56.66)ml],and the number of lymph nodes dissected was more than that in the control group[(11.86±2.44)vs.(9.26± 2.31)](all P＜0.05).Seven days after surgery,the levels of CA125,CA724,and CEA in both groups were decreased compared with those before surgery,and those in the study group[(29.88±6.15)U/ml,(11.75±7.08)U/ml,and(15.55±5.67)μg/L]were lower than those in the control group[(36.78± 5.42)U/ml,(18.35±6.24)U/ml,and(21.22±6.45)μg/L](all P＜0.05).One month after surgery,the forced vital capacity(FVC),forced expiratory volume in the first second(FEVJ,and peak expiratory flow(PEF)in both groups were decreased compared with those before surgery,and those in the study group[(2.95±0.58)L,(1.68±0.19)L,and(4.73±0.59)L/s]were higher than those in the control group[(2.72±0.65)L,(1.50±0.33)L,and(4.50±0.57)L/s](all P＜0.05).The total incidence of complications in the study group was 10.29％(7/68),which was lower than that in the control group[29.85％(20/67)],with a statistically significant difference(x2=8.067,P=0.005).Conclusion The precise positioning of 3D-CTBA in patients undergoing thoracoscopic segmentectomy for early NSCLC can reduce the levels of serum tumor markers,reduce the impact on lung function,and have fewer complications and high surgical safety.
万方数据
维普
