Risk factors for plasmapheresis or dialysis in non-diabetic patients with kidney transplantation
Objective To investigate the risk factors of plasmapheresis or dialysis in non-diabetic patients in kidney transplantation(KT).Methods A retrospective study was conducted to collect the clinical data of 507 patients who received KT in the First Affiliated Hospital of Xi'an Jiaotong University from January 2019 to December 2020,including 349 males and 158 females,aged 15 to 65 years.According to the occurrence of plasmapheresis or dialysis within 1 year after KT,the patients were divided into a treated group(49 cases)and an untreated group(458 cases).The general data of the two groups were compared by non-parametric test,chi-square test,continuity correction chi-square test,or Fisher exact probability method.The independent risk factors of plasmapheresis or dialysis were analyzed by multivariate logistic regression analysis.Results Compared with those in the untreated group,the treated group had a higher proportion of fasting plasma glucose(FPG)≥7.8 mmol/L on the 8th day after KT,a higher proportion of delayed graft function(DGF),higher levels of cystatin C(CysC)and creatinine on the 8th day after KT,and a lower glomerular filtration rate(x2=5.202 and 5.030,Z=-4.676,-5.002,and-4.937;all P＜0.05).Multivariate logistic regression analysis found that the ratio of FPG≥7.8 mmol/L on the 8th day after KT[OR=1.216,95％confidence interval(CI)1.003-1.473,P＜0.05]and CysC on the 8th day after KT(OR=1.610,95％CI 1.300-1.995,P＜0.05)were independent risk factors for plasmapheresis or dialysis.Conclusions FPG ≥7.8 mmol/L and CysC on the 8th day after KT are the independent risk factors of plasmapheresis or dialysis in non-diabetic patients with KT,so as to facilitate early assessment,prevention,and treatment.
万方数据
维普
