Clinical study on Chinese medicine Cangyi Yin in the treatment of hypertensive patients with phlegm-dampness constitution type
Objective To explore the effect of Chinese medicine Cangyi Yin in the treatment of hypertensive patients with phlegm-dampness constitution type.Methods A total of 96 hypertensive patients with phlegm-dampness constitution type treated in Guangzhou Yuexiu District Traditional Chinese Medicine Hospital from January to September 2023 were collected as the research objects,and were divided into two groups by the random number table method,with 48 patients in each group.There were 25 males and 23 females in the control group,aged(57.91± 10.78)years,and the course of disease was(5.62±1.25)years.There were 28 males and 20 females in the TCM group,aged(58.37±11.09)years,and the course of disease was(5.59±1.21)years.The control group was given routine clinical treatment,and the TCM group was given Chinese medicine Cangyi Yin on the basis of routine treatment for 12 weeks.The symptoms of phlegm-dampness constitution,levels of blood pressure,blood lipids,and inflammatory factors,and qualities of life of the two groups were compared and analyzed.Independent sample t test was used for inter-group comparison of the measurement data,paired t test was used for intra-group comparison of the measurement data,and x2 test was used for the count data.Results After treatment,the total effective rate of the TCM group[89.58％(43/48)]was higher than that of the control group[72.92％(35/48)],with a statistically significant difference(x2=4.376,P=0.036).After treatment,the symptom scores of chest tightness and abdominal distension,heavy body,mucus and phlegm at the mouth,and thick and greasy tongue coating in the TCM group were lower than those in the control group[(0.64±0.17)points vs.(2.37±0.41)points,(0.51±0.12)points vs.(2.29±0.15)points,(0.66±0.15)points vs.(2.18±0.49)points,(0.67±0.25)points vs.(2.33±0.47)points](all P＜0.05).After treatment,the levels of systolic blood pressure(SBP),diastolic blood pressure(DBP),tumor necrosis factor-α(TNF-α),and interleukin-6(IL-6)in the TCM group were lower than those in the control group[(114.65±13.49)mmHg vs.(123.58±14.25)mmHg(1 mmHg=0.133 kPa),(79.54± 9.21)mmHg vs.(85.09±10.38)mmHg,(37.19±4.87)ng/L vs.(45.18±5.33)ng/L,(21.95±3.28)ng/L vs.(27.38±3.70)ng/L](all P＜0.05).After treatment,the levels of total cholesterol(TC),triglyceride(TG),and low-density lipoprotein cholesterol(LDL-C)in the TCM group were lower than those in the control group[(4.27±1.08)mmol/L vs.(6.18±1.15)mmol/L,(1.28±0.29)mmol/L vs.(2.05±0.34)mmol/L,(2.51±0.59)mmol/L vs.(3.71±0.73)mmol/L],while the level of high-density lipoprotein cholesterol(HDL-C)was higher than that in the control group[(1.97±0.35)mmol/L vs.(1.61±0.38)mmol/L](all P＜0.05).After treatment,the scores of physiological,psychological,environmental,and social dimensions of the WHOQOL-BREF in the TCM group were higher than those in the control group[(86.93±8.17)points vs.(58.34±8.32)points,(83.27±5.19)points vs.(59.52±5.34)points,(79.84±5.47)points vs.(55.87±5.29)points,(78.65±5.41)points vs.(60.41±5.82)points](all P＜0.05).Conclusion The traditional Chinese medicine Cangyi Yin can improve the physical symptoms of hypertensive patients with phlegm-dampness constitution type,regulate the levels of blood pressure,blood lipids,and inflammatory factors,and improve their quality of life,which is worth promoting and applying.
HypertensionPhlegm-dampness constitutionChinese medicine Cangyi YinQuality of life
万方数据
维普
