Research progress of TRPV1 channel in infectious diseases
Transient receptor potential vanilloid receptor 1(TRPV1)is a non-selective cation channel in the members of the transient receptor potential family,and expresses mainly on sensory neurons.The receptor is widely distributed in vivo and has complex biological effects.In recent years,studies have found that inflammatory factors,pain signaling,body temperature,and neuronal sensitivity can be modulated by activating or inhibiting TRPV1,which may be involved in the production of infectious diseases,but it has not been used clinically.This paper reviews the physiological role of TRPV1 in infectious diseases and its regulatory mechanism,and provides new ideas for the prevention and treatment of infectious diseases.
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