Single-visit versus multiple-visit root canal treatments for patients with dental pulp disease
Objective To analyze the effects of single-visit and multiple-visit root canal treatments for patients with dental pulp disease.Methods Eighty patients with dental pulp disease treated in Liaocheng Third People's Hospital from March 2020 to March 2023 were selected for the randomized controlled trial.They were divided into an observation group and a control group by the random number table method,with 40 cases in each group.There were 21 males and 19 females in the control group;they were(40.37±8.30)years old;their disease course was(8.60± 3.15)months.There were 20 males and 20 females in the observation group;they were(40.22± 8.45)years old;their disease course was(8.55±3.20)months.The control group received multiple-visit root canal treatment,while the observation group single-visit root canal treatment.The Visual Analogue Scale(VAS)was used to assess the patients'pain level after the treatment.The analgesics-used rates,levels of inflammatory factors[interleukin-6(IL-6),interleukin-2(IL-2),high-sensitivity C-reactive protein(hs-CRP),serum osteoprotegerin,and receptor activator of nuclear factor-K B ligand(RANKL)]before and after the treatment,dental chewing function(dental occlusal force,bleeding index,and gingival index)and incidences of complications were compared between the two groups.t and x2 tests were applied.Results After the intervention,the score of VAS and analgesics-used rate in the observation group were lower than those in the control group[(2.64±0.58)vs.(3.24±0.67)and 0 vs.10.00%(4/40)],with statistical differences(t=4.282;x2=4.211;both P<0.05).Before the treatment,there were no statistical differences in the levels of IL-6,IL-2,hs-CRP,osteoprotegerin,and RANKL between the two groups(all P>0.05).After the treatment,the levels of IL-6,IL-2,hs-CRP,and RANKL in the observation group were lower than those in the control group[(1.16±0.34)ng/L vs.(1.34±0.35)ng/L,(0.29±0.04)ng/L vs.(0.33±0.06)ng/L,(1.14± 0.11)mg/L vs.(1.65±0.22)mg/L,and(0.35±0.06)ng/L vs.(0.39±0.08)ng/L];the level of osteoprotegerin in the observation group were higher than that in the control group[(0.43± 0.08)pg/L vs.(0.36±0.07)pg/L];there were statistical differences(t=2.233,3.508,13.114,2.530,and 4.165;all P<0.05).Before the treatment,there were no statistical differences in the dental occlusal force,bleeding index,and gingival index between the two groups(all P>0.05).After the treatment,the bleeding index and gingival index in the observation group were lower than those in the control group[(0.48±0.10)vs.(0.90±0.19)and(0.47±0.09)vs.(0.76±0.15)];the dental occlusal force in the observation group was higher than that in the control group[(140.18±11.85)lbs vs.(116.75±9.97)lbs];there were statistical differences(t=12.372,10.485,9.569;all P<0.05).After the intervention,the total incidence of complications in the observation group was lower than that in the control group[5.00%(2/40)vs.22.50%(9/40)],with statistical difference(x2=5.165,P=0.023).Conclusion Single-visit root canal treatment is more effective in reducing pain and decreasing inflammation levels in patients with dental pulp disease than multiple-visit treatment.