Advances in single-cell RNA sequencing in kidney disease
Single-cell RNA sequencing(scRNA-seq)technology has brought many new discoveries to biomedical research,enabling high-resolution,high-throughput,and repeatable transcriptional analysis to identify new cell types and form cell maps.However,traditional sequencing methods can only reflect the overall level of gene expression of all cells in the samples and cannot reveal the heterogeneity of gene expression between individual cells.This article elaborates on the development history of scRNA-seq technology and outlines its potential application to reveal the mechanisms of kidney diseases,which is beneficial for diagnosis and treatment of kidney disease.
Single cell sequencingSingle-cell RNA sequencingIgA nephropathyDiabetic nephropathyMembranous nephropathyKidney transplantationRenal fibrosisProgress
国家科技期刊平台
NSTL
万方数据
