摘要
溃疡性结肠炎作为一种非特异性的肠道炎症疾病,主要影响直肠和结肠,通常具有慢性、迁延性、反复发作的特征.其病变部位仅限于黏膜层或肌层,多发生溃疡,肠壁可能会出现不同程度的出血、水肿等.患者临床症状多为间歇性腹泻、便中带黏液及脓血、腹痛、里急后重等.该病治愈困难、复发率高、癌变率高、与结肠癌的发生关系密切.西医药物治疗多采用抗炎药、糖皮质激素、免疫抑制剂等治疗,同时也可以采用一般性治疗.一般性治疗包括休息、营养支持等.一些符合手术指征的患者可施行结肠切除等术式.随着中医外科学的不断发展,中医药的内外治法对溃疡性结肠炎的分型论治和整体调理均具有独特优势和良好疗效.本文概括了近年来中西医对于溃疡性结肠炎的临床诊治和研究情况.
Abstract
Ulcerative colitis is a non-specific intestinal inflammatory disease that mainly affects the rectum and colon,typically characterized by chronic,persistent,and recurrent symptoms.The lesion is limited to the mucosal layer or muscular layer,mainly characterized by ulcers,and may be accompanied by varying degrees of intestinal wall congestion,edema,and bleeding.The patients'clinical symptoms include intermittent diarrhea,feces with mucus and pus,abdominal pain,and urgency.This disease is difficult to cure,has a high recurrence rate,and a high cancer transformation rate,and is closely related to the incidence of colon cancer.Western medicine medication often uses mesalazine enteric coated tablets,glucocorticoids,immunosuppressants,etc.Generally,treatments,such as rest and nutritional support,are used.For patients who meet surgical indications,total colectomy and ileal pouch anal anastomosis can be used.With the continuous development of traditional Chinese medicine surgery,the internal and external treatment methods of traditional Chinese medicine have unique advantages and good therapeutic effects in the classification and treatment of ulcerative colitis.This article summarizes the clinical diagnosis,treatment,and research status of ulcerative colitis in recent years.
基金项目
全国名老中医药专家传承工作室建设项目(czbkjf20170053)
安徽省省级中医优势特色专科建设项目(十四五)(zyyfw20210087)
安徽省青年领军后备人才项目(2020qnqhxz20220011)
维普
万方数据