Research progress of traditional Chinese patent medicine related liver injury
Drug-induced liver injury refers to liver damage caused by chemicals,biological products,and traditional Chinese medicine and its preparations,and is one of the common adverse drug reactions in clinical practice.In recent years,the clinical reports of traditional Chinese patent medicine containing Polygoni Multiflori Radix,Psoralea corylifolia Linn,and Epimedium brevicornu Maxim causing liver injury have gradually increased.The researches on the causes and mechanisms of liver injury caused by them have received extensive attention and made some progress.This article mainly reviews the causes and pathogenesis of traditional Chinese patent medicine related liver injury containing such components.