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中成药相关肝损伤研究进展

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药物性肝损伤是指由化学药品、生物制品、中草药及其制剂等所导致的肝损伤,是临床常见的药物不良反应之一.近年来,含何首乌、补骨脂、淫羊藿的中成药导致肝损伤的临床报道逐渐增多,其导致肝损伤的原因及机制受到广泛关注,并取得一定进展.本文主要对含此类组分的中成药及其肝损伤的原因、发病机制等进行综述.
Research progress of traditional Chinese patent medicine related liver injury
Drug-induced liver injury refers to liver damage caused by chemicals,biological products,and traditional Chinese medicine and its preparations,and is one of the common adverse drug reactions in clinical practice.In recent years,the clinical reports of traditional Chinese patent medicine containing Polygoni Multiflori Radix,Psoralea corylifolia Linn,and Epimedium brevicornu Maxim causing liver injury have gradually increased.The researches on the causes and mechanisms of liver injury caused by them have received extensive attention and made some progress.This article mainly reviews the causes and pathogenesis of traditional Chinese patent medicine related liver injury containing such components.

Liver injuryTraditional Chinese patent medicinePolygoni Multiflori RadixPsoralea corylifolia LinnEpimedium brevicornu MaximProgress

何祥琴、杨芳、丁国锋

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滨州医学院附属医院感染科,滨州 256600

肝损伤 中成药 何首乌 补骨脂 淫羊藿 进展

山东省药品不良反应监测中心委托项目

2022SDADRKY28

2024

国际医药卫生导报
中华医学会,国际医药卫生导报社

国际医药卫生导报

影响因子:0.781
ISSN:1007-1245
年,卷(期):2024.30(9)
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