Efficacy of Sanyinjiao warm acupuncture combined with exercise therapy on post-stroke depression patients
Objective To explore the efficacy of Sanyinjiao warm acupuncture combined with exercise therapy in patients with post-stroke depression.Methods A prospective study design was used.Eighty patients with post-stroke depression admitted to Xingyuan Hospital of Yulin from January 2020 to October 2023 were included.The patients were divided into two groups using the balloting method,with odd numbers assigned to the control group(40 cases)and even numbers to the experimental group(40 cases).There were 20 males and 20 females in the experimental group;the age was 48-72(61.87±8.74)years old;the depression degree was mild in 20 cases and moderate in 20 cases;the type of stroke was cerebral infarction in 30 cases and cerebral hemorrhage in 10 cases.There were 21 males and 19 females in the control group;the age was 47-71(60.13± 8.49)years old;the degree of depression was mild in 19 cases and moderate in 21 cases;the type of stroke was cerebral infarction in 31 cases and cerebral hemorrhage in 9 cases.The control group received exercise therapy,and the experimental group received Sanyinjiao warm acupuncture in addition to exercise therapy,over a treatment course of 6 weeks.The changes in traditional Chinese medicine(TCM)symptom score,Montgomery-Asberg Depression Rating Scale(MADRS)score,levels of monoamine neurotransmitters[dopamine(DA),5-serotonin(5-HT),and norepinephrine(NE)],Carroll Upper Extremity Functional Test(UEFT)score,Burke Lateropulsion Scale(BLS)score,Trunk Control Test(TCT)score,score of Borg scale for perceived exertion,Athens Insomnia Scale(AIS)score,and Hamilton Depression Rating Scale(HAMD)insomnia subsection score were compared between the two groups.Independent sample t test,paired sample t test,and x2 test were used.Results After 6 weeks of treatment,the TCM symptom score[(7.39±2.13)points]and MADRS score[(11.58±1.53)points]of the experimental group were lower than those of the control group[(9.65±3.34)points and(13.34±1.60)points](both P＜0.05).The levels of DA[(74.08±7.60)ng/L],5-HT[(280.96±34.85)μg/L],and NE[(45.44±6.51)μg/L]in the experimental groups were higher than those in the control group[(65.19±7.01)ng/L,(248.09±30.21)μg/L,and(37.21±5.48)μg/L](all P＜0.05).The UEFT score[(35.81±6.17)points]and TCT score[(75.34±16.55)points]in the experimental groups were higher than those in the control group[(23.42±3.63)points and(36.32± 13.06)points](both P＜0.05).The BLS score[(4.85±1.86)points],AIS score[(4.64±1.36)points],and HAMD insomnia subsection score[(1.77±0.85)points]in the experimental groups were lower than those in the control group[(9.18±1.74)points,(6.52±1.63)points,and(2.62±0.83)points](all P＜0.05).The Borg scale score of the experimental group[(3.77±0.90)points]after walking was lower than that of the control group[(5.34±1.27)points](P＜0.05).Conclusion Sanyinjiao warm acupuncture combined with exercise therapy significantly improves the TCM syndromes,emotional state,neurotransmitter level,upper limb function,trunk control ability,fatigue level,and sleep quality in patients with post-stroke depression,making it a valuable treatment option.
万方数据
维普
