Evaluation of the application of comprehensive high quality nursing intervention in intraperitoneal hyperthermic perfusion chemotherapy for colon cancer
Objective To study the clinical value of comprehensive high quality care intervention in colon cancer patients during intraperitoneal hyperthermic perfusion chemotherapy.Methods A prospective study was conducted.A total of 100 colon cancer patients who underwent intraperitoneal hyperthermic perfusion chemotherapy in Guangzhou First People's Hospital from August 2022 to July 2023 were divided into two groups using the random number table method.In the control group,there were 28 males and 22 females,and the age was 42-76(58.36±2.71)years old.In the observation group,there were 29 males and 21 females,and the age was 40-73(58.15± 2.58)years old.The control group received routine chemotherapy care,and the observation group received comprehensive high-quality nursing intervention.The cancer-related fatigue,pain degree,sleep qualities,psychological state scores,immune function,inflammatory response related indicators,incidences of adverse reactions,and nursing satisfaction were compared between the two groups before and after 7 days of nursing.Statistical methods used were t test and x2 test.Results After nursing,the scores of Visual Analogue Scale(VAS),Pittsburgh Sleep Quality Index(PSQI),and Cancer-Related Fatigue Assessment Scale of the observation group were lower than those of the control group[(2.43±0.18)points vs.(4.16±0.25)points,(2.43±0.18)points vs.(7.16±1.25)points,(2.42±0.06)points vs.(5.16±0.17)points],with statistically significant differences(t=39.71,26.48,and 107.47,all P＜0.05).After nursing,the scores of Self-rating Anxiety Scale(SAS)and Self-rating Depression Scale(SDS)in the observation group were lower than those in the control group[(17.19± 1.08)points vs.(33.52±1.64)points,(18.43±1.68)points vs.(32.16±2.05)points],with statistically significant differences(t=58.80 and 36.63,both P＜0.05).The related indicators of immune function and inflammatory response in the observation group after nursing were better than those in the control group,with statistically significant differences(all P＜0.05).The incidences of adverse reactions(immunosuppression,phlebitis,and gastrointestinal reactions)in the observation group were lower than those in the control group,with statistically significant differences(x2=10.19,7.11,and 13.56,all P＜0.05).The nursing satisfaction of the observation group was higher than that of the control group[94.00％(47/50)vs.80.00％(40/50)],with a statistically significant difference(x2=4.33,P＜0.05).Conclusion Colon cancer patients receive comprehensive high quality nursing intervention during intraperitoneal hyperthermic perfusion chemotherapy,which helps to improve the immune function and sleep quality,control the pain,cancer-related fatigue,and inflammation,reduce the adverse reactions,and keep a good attitude,so as to improve the nursing satisfaction.
Colon cancerIntraperitoneal hyperthermic perfusion chemotherapyComprehensive high quality carePainFatigue
万方数据
维普
