The nursing experience of three children with grade Ⅳ graft-versus-host disease after hematopoietic stem cell transplantation was summarized.The nursing points were as below:making a nursing plan for the medical team and providing full process management;paying attention to environmental management and ensuring protective isolation;taking good care of the skin wound,fixing the central venous catheter,and providing nutritional support and psychological care.After effective treatment and careful care,the affected areas of the children's skin lesions basically healed.
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