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METS-IR与心血管疾病研究进展

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随着生活水平提高,心血管疾病发病率及病死率逐年上升,已成为重要的公共卫生问题。胰岛素抵抗状态与心血管疾病发生及发展中的病理生理过程密切相关。深入研究二者之间的内在联系对于心血管疾病的早期预防、治疗和随访至关重要。传统的胰岛素抵抗检测方法操作繁琐、耗时,价格昂贵,不适合在医院开展,更无法在大规模人群中推广。胰岛素抵抗代谢评分(METS-IR)是一个新型的胰岛素抵抗预测指标,其反映胰岛素抵抗具有高效及简便的特点,并且METS-IR升高与心血管疾病发生及不良心血管预后具有正相关性。基于此,本文就METS-IR对常见心血管疾病的诊断及临床应用价值进行综述。
Advances in METS-IR and cardiovascular diseases
With the improvement of living standards,the incidence and mortality of cardiovascular diseases are increasing year by year and have become an important public health problem.Insulin resistance status is closely related to the pathophysiologic process in the occurrence and development of cardiovascular diseases.In-depth study of the intrinsic link between insulin resistance and cardiovascular diseases is essential for early prevention,treatment,and follow-up of cardiovascular diseases.Traditional insulin resistance testing methods are cumbersome,time-consuming,and expensive,making them unsuitable for hospitals,not to mention being unable to be generalized in large-scale populations.Metabolic Score for Insulin Resistance(METS-IR)is a new type of predictors of insulin resistance,and METS-IR reflects insulin resistance with high efficiency and simplicity.Moreover,elevated METS-IR is positively correlated with cardiovascular diseases and poor cardiovascular prognosis.Based on this,this article summarizes the diagnostic and clinical value of METS-IR in common cardiovascular diseases.

Cardiovascular diseasesMETS-IRInsulin resistanceProgress

王新宇、郭义山、刘茜、王东

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滨州医学院附属医院心血管内科,滨州 256603

心血管疾病 胰岛素抵抗代谢评分 胰岛素抵抗 进展

国家自然科学基金滨州医学院科技计划

82100244BY2019KJ39

2024

国际医药卫生导报
中华医学会,国际医药卫生导报社

国际医药卫生导报

影响因子:0.781
ISSN:1007-1245
年,卷(期):2024.30(14)