Clinical efficacy of Xiaozhong decoction in treatment of postoperative complications of patients with mixed hemorrhoids
Objective To observe the clinical effect of Xiaozhong decoction in the treatment of postoperative complications of patients with mixed hemorrhoids.Methods One hundred and twenty patients with mixed hemorrhoids treated at Minxian Hospital of Traditional Chinese Medicine from February 2023 to January 2024 were selected for the randomized controlled trial.The patients were divided into a control group and an observation group by the random number table method,with 60 cases in each group.There were 31 males and 29 females in the control group;they were(43.15±13.19)years old;their disease course was(3.70±1.95)years;their body mass index was(22.70±2.25)kg/m2.There were 28 males and 32 females in the observation group;they were(42.68±14.80)years old;their disease course was(3.90±2.36)years;their body mass index was(22.91±2.13)kg/m2.Both groups received routine postoperative treatment.The control group were treated with potassium permanganate fumigation,and the observation group with Xiaozhong decoction fumigation.Five days were one treatment course;both groups were treated two courses.After the treatment,the total effective rates were compared between the two groups.The scores of clinical symptoms day 1,3,7,and 11 after the operation and the levels of tumor necrosis factor-α(TNF-α),interleukin-1β(IL-1β),and interleukin-6(IL-6)before and after the treatment in both groups were recorded.t and x2 tests were applied.Results The total effective rate in the control group was 75.0％(45/60),and that in the observation group was 91.7％(55/60),with a statistical difference(P＜0.05).The scores of pain,wound exudate,and anal prolapse day 3,7,and 11 after the operation in the observation group were lower than those in the control group[day 3 after the operation:(4.93±1.07)vs.(6.13±1.28),(1.85±0.40)vs.(2.07±0.68),and(2.02±0.75)vs.(2.35±0.71);day 7 after the operation:(3.53±1.11)vs.(4.13±0.93),(1.47±0.54)vs.(1.87±0.85),and(1.53±0.50)vs.(1.87±0.72);day 11 after the operation:(1.62±1.11)vs.(2.28±1.51),(0.75±0.79)vs.(1.21±0.72),and(0.63±0.58)vs.(0.98±0.83)],with statistical differences(all P＜0.05).After the treatment,the levels of TNF-α,IL-1β,and IL-6 in the observation group were lower than those in the control group[(2.75±1.01)ng/L vs.(5.25±1.87)ng/L,(5.75±2.00)ng/L vs.(9.78±2.82)ng/L,and(8.14±2.14)ng/L vs.(12.68±4.13)ng/L],with statistical differences(all P＜0.05).Conclusion Xiaozhong decoction in the treatment of postoperative complications of patients with mixed hemorrhoids is effective,so it is worthy of promotion.
万方数据
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